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Choose from exclusive hotel collection
We offer thousands of Panama City hotels and accommodations from world's renowned hotel chains to unique gems of the region you won’t find anywhere else.
Enjoy seamless booking experience
Once you choose your best place to stay, take a minute to complete a quick reservation form and get an instant confirmation letter to your email address.
Benefit from flexible travel options
We provide the most flexible cancellation options, so you get your deposit back in case of a change of plans or other unforeseen circumstances.
Welcome to Panama City
Explore the vibrant and cosmopolitan Panama City! With its modern skyline, colonial architecture, mouth-watering cuisine, and friendly locals, this Central American gem attracts visitors from all around the world. Be sure to check out the Panama Canal, Casco Viejo, and Ancon Hill for unforgettable experiences. Don't wait, book your trip to Panama City today for an unforgettable adventure!
What our users say about Panama City hotels
The great location within walking distance of Alvin's Island and the luxurious room with extremely comfortable beds make this place a top choice for a relaxing stay.
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The staff here were very friendly, the location is fantastic with close proximity to the beach and local restaurants, the building and rooms are nice with a garden view, and there is a poolside bar available.
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Loved having a full-sized fridge in our rooms! 🙌
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Impressive and spacious room 😊. the stay here matched our expectations and was enjoyable while on vacation.
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The staff here is friendly and the rooms are comfortable at this family-run hotel.
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Hard-working stuff and a superb breakfast including variety of eggs, fresh fruit and sausages.
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Generally, the place was impressive and had attentive staff from porter. Loved our rooms on the lower floors. Its location was indeed magnificent and handy and only 5 minutes walk from a history museum. It was across the fairly nice area. The hotel had a fantastic bar and a good restaurant.
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This place is clean, offers ocean and state park views, has a super friendly staff team, and is definitely a luxurious choice when visiting.
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Booked a room with a nice view and the meals were outstanding during our stay here.
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Staff and location were excellent and I loved that the place was clean. Booked a room with fantastic views of the bay. There was a great restaurant in the hotel...
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Save time on your trip arrangements by booking one of our hand-picked hotels
Top 5-star hotels
Exclusive 3-star hotels
Quality 2-star hotels
Indulge yourself with luxury and comfort as you explore the exciting attractions of Panama City.
Enjoy truly authentic experiences without compromising comfort and convenience.
- Best Western Plus Panama City Hotel
- Days Inn By Wyndham Panama City
- Hotel Indigo - Panama City Marina By Ihg
- Comfort Suites Panama City Near Tyndall Afb
- Holiday Inn Panama City By Ihg
- Comfort Inn & Suites Panama City North
- Courtyard By Marriott Panama City
- Hilton Garden Inn Panama City
- Towneplace Suites By Marriott Panama City
- Emerald Beach Resort By Resort Collection
- Raven Beach House Hotel
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Discover the hidden gems of Panama City by booking one of its budget-friendly hotels.
- Suburban Studios Near Panama City Beach
- Hathaway Inn
- Rodeway Inn Panama City
- Candlewood Suites Panama City - Tyndall Afb By Ihg
- Quality Inn & Suites Near Panama City Beach
- Baymont By Wyndham Panama City Beach
- Holiday Inn Express Hotel & Suites Panama City-Tyndall
- Days Inn By Wyndham Panama City/Callaway
- Super 8 By Wyndham Panama City
- American Quality Lodge
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Travelers’ choice
Check out the most booked accommodations to find reliable places that our users have tried and tested.
- Pearl Cottage
- Charming 3-Bedroom Home In Beautiful Panama City
- Luxury Bathroom Home With Game Room 25 Mins To Pcb
- Panama City Home With Beach Gear And 2 Bikes
- Luxe Pool Casita W Saltwater Pool 25 Min To Pcb Apartment
- Stylish 3Br 2Ba House Minutes From Pcb - Book Now Villa
- Dreami Stays Panama City - 2Br Retreat Near Downtown, Beaches, & Hot Spots
- Sunny Panama City Escape With Pool And Deck!
- Adorable 1 Bdr With Full Kitchen Deck Washer Dryer
- The Splash Pad Sleeps 13 W Pool Patio And Garage
- Escape To Paradise W Saltwater Pool 25 Min To Pcb
- Pc Poolside Palms Apartment
- Cove Cottage - 3 Bedroom Withprivate Pool, Sleeps 6, Quiet Community, Close To Fishing Marinas, Home
- Vacation In This Gorgeous 2-Story Home! 3 Bedroom 3 Ba! Sleeps 8!
- Sunrise Beach Resort V
- South Walton Condos II
- Lovely Panama City Cottage Walk To Bayside Beach!
- Beachfront Panama City Condo With Balcony And Views!
- Charming 3Br Home With Free Parking & Game Room
- Modern Getaway North Of Panama City Beach
- Down By The Bay W Hot Tub, 2 Blocks 2 Beaches, Game Room, Reading Nook, Dog-Friendly, Historic Charm
- Pool And Beach Access Sunnyside 55 In Pcb!
- Pinnacle Port Penthouse 10
- Ocean'S Shimmer Sanctuary
- A Love Of Leisure
- Cozy 4Br Panama City Retreat! Games & Beach Gear!
- Lux Min To Beach And Hospital With Hot Tub
- Renovated Townhome By The Bay
- Beach House With Private Pool - Sunny Sands By Panhandle Getaways
- Down By The Bay St Andrews Gem Villa
- Luxe Guest Suite Near The Emerald Coast Of Pcb
- Loaded House And Guest House W Game Room Gym
- Blue Tide Hideaway - Golf Cart, Sznl Hot Tub, Pets Ok, Free Daily Activities, & More!
- 13 Mi To St Andrews State Park Cabin With Patio!
- Salt Water Pool, Game Room, King Bed &Pet Friendly
- Destin Towers 1E Apartment
- 7 Mi To Dtwn Panama City Family Home With Patio
- Ocean Spray Villa
- Nautical Nirvana-Waterfront Joys From Sunrise Paddles To Hot Tub Sunsets
- Laid-Back - Private Pool, 4 Min Walk To Beach, Close To 30A, Free Daily Activities
- Bliss By The Bay Villa
- Two Spaces In One Main House And Guest House 25 Min To Pcb
- Dream On - Style & Comfort Near Historic Downtown
- A Block Away From Beach/Harbor/Fine Restaurants
- Regency Towers 1122 'Seas The Day' Villa
- 17 Trigger Trail West Villa
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